Response to ‘Increase of nerve growth factor levels in the human herniated intervertebral disc: can annular rupture trigger discogenic back pain?’ – authors’ reply

نویسندگان

  • Yasuchika Aoki
  • Arata Nakajima
  • Seiji Ohtori
  • Hiroshi Takahashi
  • Fusako Watanabe
  • Masato Sonobe
  • Fumiaki Terajima
  • Masahiko Saito
  • Kazuhisa Takahashi
  • Tomoaki Toyone
  • Atsuya Watanabe
  • Takayuki Nakajima
  • Makoto Takazawa
  • Koichi Nakagawa
چکیده

Response to ‘Increase of nerve growth factor levels in the human herniated intervertebral disc: can annular rupture trigger discogenic back pain?’ – authors’ reply Yasuchika Aoki, Arata Nakajima, Seiji Ohtori, Hiroshi Takahashi, Fusako Watanabe, Masato Sonobe, Fumiaki Terajima, Masahiko Saito, Kazuhisa Takahashi, Tomoaki Toyone, Atsuya Watanabe, Takayuki Nakajima, Makoto Takazawa and Koichi Nakagawa

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Response to ‘Increase of nerve growth factor levels in the human herniated intervertebral disc: can annular rupture trigger discogenic back pain?’

We have read with a great interest the published article by Aoki and colleagues entitled ‘Increase of nerve growth factor levels in the human herniated intervertebral disc: can annular rupture trigger discogenic back pain?’ [1]. The authors suggest that nerve growth factor (NGF) increases in herniated discs, and may play an important role in the generation of discogenic pain. However, we think ...

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Increase of nerve growth factor levels in the human herniated intervertebral disc: can annular rupture trigger discogenic back pain?

INTRODUCTION Nerve growth factor (NGF) has an important role in the generation of discogenic pain. We hypothesized that annular rupture is a trigger for discogenic pain through the action of NGF. In this study, the protein levels of NGF in discs from patients with disc herniation were examined and compared with those from discs of patients with other lumbar degenerative disc diseases. METHODS...

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عنوان ژورنال:

دوره 17  شماره 

صفحات  -

تاریخ انتشار 2015